Cargando…

Criteria and Procedures for Breast Conserving Surgery

AIM: Emphasizing circumstances that determine increasingly popular surgical approach of breast conserving surgery (BCS), used in lower grade breast tumors, while maintaining survival that is found when more radical procedures are used. PATIENTS AND METHODS: Several leading oncological protocols in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Fajdic, Josip, Djurovic, Drazen, Gotovac, Nikola, Hrgovic, Zlatko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AVICENA 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610577/
https://www.ncbi.nlm.nih.gov/pubmed/23572855
http://dx.doi.org/10.5455/AIM.2013.21.16-19
_version_ 1782264469682913280
author Fajdic, Josip
Djurovic, Drazen
Gotovac, Nikola
Hrgovic, Zlatko
author_facet Fajdic, Josip
Djurovic, Drazen
Gotovac, Nikola
Hrgovic, Zlatko
author_sort Fajdic, Josip
collection PubMed
description AIM: Emphasizing circumstances that determine increasingly popular surgical approach of breast conserving surgery (BCS), used in lower grade breast tumors, while maintaining survival that is found when more radical procedures are used. PATIENTS AND METHODS: Several leading oncological protocols in the world are compared, using PubMed database, and our own experience. Data gathered are compared to conclusions of Consensus Conference on Breast Conservation (Milan, 2005). Furthermore, surgical contraindications found in our everyday work are considered, having in mind satisfactory cosmetic outcome, as well as keeping the 1 cm border of “clear” edges. Such more practical problems of edge detection can compromise BCS results. RESULTS: After observing several relevant protocols, we found very high frequency of mastectomy vs. BCS, despite the fact that stage of disease was low. We also found only 20% of absolute contraindications for BCS. Most frequent contraindication for BCS was multicentricity of the tumor (with micro calcifications), especially in ductal in situ carcinoma. CONCLUSION: BCS followed by radiation therapy with tumor-free edges is standard procedure in treatment of T1 and small T2 breast cancers. This approach implies higher risk of local recurrence (LR), although local recurrence is low (1% per year), with rates of survival similar to radical procedures.
format Online
Article
Text
id pubmed-3610577
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher AVICENA
record_format MEDLINE/PubMed
spelling pubmed-36105772013-04-09 Criteria and Procedures for Breast Conserving Surgery Fajdic, Josip Djurovic, Drazen Gotovac, Nikola Hrgovic, Zlatko Acta Inform Med Original Paper AIM: Emphasizing circumstances that determine increasingly popular surgical approach of breast conserving surgery (BCS), used in lower grade breast tumors, while maintaining survival that is found when more radical procedures are used. PATIENTS AND METHODS: Several leading oncological protocols in the world are compared, using PubMed database, and our own experience. Data gathered are compared to conclusions of Consensus Conference on Breast Conservation (Milan, 2005). Furthermore, surgical contraindications found in our everyday work are considered, having in mind satisfactory cosmetic outcome, as well as keeping the 1 cm border of “clear” edges. Such more practical problems of edge detection can compromise BCS results. RESULTS: After observing several relevant protocols, we found very high frequency of mastectomy vs. BCS, despite the fact that stage of disease was low. We also found only 20% of absolute contraindications for BCS. Most frequent contraindication for BCS was multicentricity of the tumor (with micro calcifications), especially in ductal in situ carcinoma. CONCLUSION: BCS followed by radiation therapy with tumor-free edges is standard procedure in treatment of T1 and small T2 breast cancers. This approach implies higher risk of local recurrence (LR), although local recurrence is low (1% per year), with rates of survival similar to radical procedures. AVICENA 2013-03 /pmc/articles/PMC3610577/ /pubmed/23572855 http://dx.doi.org/10.5455/AIM.2013.21.16-19 Text en © Avicena
spellingShingle Original Paper
Fajdic, Josip
Djurovic, Drazen
Gotovac, Nikola
Hrgovic, Zlatko
Criteria and Procedures for Breast Conserving Surgery
title Criteria and Procedures for Breast Conserving Surgery
title_full Criteria and Procedures for Breast Conserving Surgery
title_fullStr Criteria and Procedures for Breast Conserving Surgery
title_full_unstemmed Criteria and Procedures for Breast Conserving Surgery
title_short Criteria and Procedures for Breast Conserving Surgery
title_sort criteria and procedures for breast conserving surgery
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610577/
https://www.ncbi.nlm.nih.gov/pubmed/23572855
http://dx.doi.org/10.5455/AIM.2013.21.16-19
work_keys_str_mv AT fajdicjosip criteriaandproceduresforbreastconservingsurgery
AT djurovicdrazen criteriaandproceduresforbreastconservingsurgery
AT gotovacnikola criteriaandproceduresforbreastconservingsurgery
AT hrgoviczlatko criteriaandproceduresforbreastconservingsurgery