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Productive Homologous and Non-homologous Recombination of Hepatitis C Virus in Cell Culture

Genetic recombination is an important mechanism for increasing diversity of RNA viruses, and constitutes a viral escape mechanism to host immune responses and to treatment with antiviral compounds. Although rare, epidemiologically important hepatitis C virus (HCV) recombinants have been reported. In...

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Detalles Bibliográficos
Autores principales: Scheel, Troels K. H., Galli, Andrea, Li, Yi-Ping, Mikkelsen, Lotte S., Gottwein, Judith M., Bukh, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610614/
https://www.ncbi.nlm.nih.gov/pubmed/23555245
http://dx.doi.org/10.1371/journal.ppat.1003228