Genome-Wide Testing of Putative Functional Exonic Variants in Relationship with Breast and Prostate Cancer Risk in a Multiethnic Population

Rare variation in protein coding sequence is poorly captured by GWAS arrays and has been hypothesized to contribute to disease heritability. Using the Illumina HumanExome SNP array, we successfully genotyped 191,032 common and rare non-synonymous, splice site, or nonsense variants in a multiethnic s...

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Detalles Bibliográficos
Autores principales: Haiman, Christopher A., Han, Ying, Feng, Ye, Xia, Lucy, Hsu, Chris, Sheng, Xin, Pooler, Loreall C., Patel, Yesha, Kolonel, Laurence N., Carter, Erin, Park, Karen, Le Marchand, Loic, Van Den Berg, David, Henderson, Brian E., Stram, Daniel O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610631/
https://www.ncbi.nlm.nih.gov/pubmed/23555315
http://dx.doi.org/10.1371/journal.pgen.1003419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610631/
https://www.ncbi.nlm.nih.gov/pubmed/23555315
http://dx.doi.org/10.1371/journal.pgen.1003419

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