Re-Evaluation of PD-1 Expression by T Cells as a Marker for Immune Exhaustion during SIV Infection

PD-1 expression is generally associated with exhaustion of T cells during chronic viral infections based on the finding that PD-1 expressing cells respond poorly to antigen activation and blockade of PD-1/PD-ligand interaction restores such antigen specific responses in vitro. We tested this hypothe...

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Detalles Bibliográficos
Autores principales: Hong, Jung Joo, Amancha, Praveen K., Rogers, Kenneth, Ansari, Aftab A., Villinger, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610666/
https://www.ncbi.nlm.nih.gov/pubmed/23555918
http://dx.doi.org/10.1371/journal.pone.0060186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610666/
https://www.ncbi.nlm.nih.gov/pubmed/23555918
http://dx.doi.org/10.1371/journal.pone.0060186

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