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Re-Evaluation of PD-1 Expression by T Cells as a Marker for Immune Exhaustion during SIV Infection
PD-1 expression is generally associated with exhaustion of T cells during chronic viral infections based on the finding that PD-1 expressing cells respond poorly to antigen activation and blockade of PD-1/PD-ligand interaction restores such antigen specific responses in vitro. We tested this hypothe...
Autores principales: | Hong, Jung Joo, Amancha, Praveen K., Rogers, Kenneth, Ansari, Aftab A., Villinger, Francois |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610666/ https://www.ncbi.nlm.nih.gov/pubmed/23555918 http://dx.doi.org/10.1371/journal.pone.0060186 |
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