Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis

Anti-tumor necrosis factor alpha (anti-TNF) biologic therapy is a widely used treatment for rheumatoid arthritis (RA). It is unknown why some RA patients fail to respond adequately to anti-TNF therapy, which limits the development of clinical biomarkers to predict response or new drugs to target ref...

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Detalles Bibliográficos
Autores principales: Cui, Jing, Stahl, Eli A., Saevarsdottir, Saedis, Miceli, Corinne, Diogo, Dorothee, Trynka, Gosia, Raj, Towfique, Mirkov, Maša Umiċeviċ, Canhao, Helena, Ikari, Katsunori, Terao, Chikashi, Okada, Yukinori, Wedrén, Sara, Askling, Johan, Yamanaka, Hisashi, Momohara, Shigeki, Taniguchi, Atsuo, Ohmura, Koichiro, Matsuda, Fumihiko, Mimori, Tsuneyo, Gupta, Namrata, Kuchroo, Manik, Morgan, Ann W., Isaacs, John D., Wilson, Anthony G., Hyrich, Kimme L., Herenius, Marieke, Doorenspleet, Marieke E., Tak, Paul-Peter, Crusius, J. Bart A., van der Horst-Bruinsma, Irene E., Wolbink, Gert Jan, van Riel, Piet L. C. M., van de Laar, Mart, Guchelaar, Henk-Jan, Shadick, Nancy A., Allaart, Cornelia F., Huizinga, Tom W. J., Toes, Rene E. M., Kimberly, Robert P., Bridges, S. Louis, Criswell, Lindsey A., Moreland, Larry W., Fonseca, João Eurico, de Vries, Niek, Stranger, Barbara E., De Jager, Philip L., Raychaudhuri, Soumya, Weinblatt, Michael E., Gregersen, Peter K., Mariette, Xavier, Barton, Anne, Padyukov, Leonid, Coenen, Marieke J. H., Karlson, Elizabeth W., Plenge, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610685/
https://www.ncbi.nlm.nih.gov/pubmed/23555300
http://dx.doi.org/10.1371/journal.pgen.1003394

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