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Genetic Characterization of Natural Variants of Vpu from HIV-1 Infected Individuals from Northern India and Their Impact on Virus Release and Cell Death

BACKGROUND: Genetic studies reveal that vpu is one of the most variable regions in HIV-1 genome. Functional studies have been carried out mostly with Vpu derived from laboratory adapted subtype B pNL 4-3 virus. The rationale of this study was to characterize genetic variations that are present in th...

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Detalles Bibliográficos
Autores principales: Verma, Sachin, Ronsard, Larance, Kapoor, Richa, Banerjea, Akhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610703/
https://www.ncbi.nlm.nih.gov/pubmed/23555649
http://dx.doi.org/10.1371/journal.pone.0059283