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Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung

Pneumococcal carriage is both immunising and a pre-requisite for mucosal and systemic disease. Murine models of pneumococcal colonisation show that IL-17A-secreting CD4(+) T-cells (Th-17 cells) are essential for clearance of pneumococci from the nasopharynx. Pneumococcal-responding IL-17A-secreting...

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Detalles Bibliográficos
Autores principales:	Wright, Adam K. A., Bangert, Mathieu, Gritzfeld, Jenna F., Ferreira, Daniela M., Jambo, Kondwani C., Wright, Angela D., Collins, Andrea M., Gordon, Stephen B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610738/ https://www.ncbi.nlm.nih.gov/pubmed/23555269 http://dx.doi.org/10.1371/journal.ppat.1003274

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