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Pirh2 E3 Ubiquitin Ligase Modulates Keratinocyte Differentiation Through p63
p63, a homologue of the tumor suppressor p53, is essential for the development of epidermis and limb. p63 is highly expressed in epithelial cell layer and acts as a molecular switch that initiates epithelial stratification. However, the mechanisms controlling p63 protein level is still far from full...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610774/ https://www.ncbi.nlm.nih.gov/pubmed/23235527 http://dx.doi.org/10.1038/jid.2012.466 |