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Phosphorylated IκBα Predicts Poor Prognosis in Activated B-Cell Lymphoma and Its Inhibition with Thymoquinone Induces Apoptosis via ROS Release

Activated B-cell lymphoma (ABC), one of the three subtypes of Diffuse Large B-cell Lymphoma (DLBCL) has the worst survival rate after upfront chemotherapy and is characterized by constitutively activated NFκB. We therefore studied the role of NFκB In a cohort of clinical DLBCL samples and ABC cell l...

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Detalles Bibliográficos
Autores principales:	Hussain, Azhar R., Uddin, Shahab, Ahmed, Maqbool, Al-Dayel, Fouad, Bavi, Prashant P., Al-Kuraya, Khawla S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610815/ https://www.ncbi.nlm.nih.gov/pubmed/23555990 http://dx.doi.org/10.1371/journal.pone.0060540

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