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Targeted Deletion of the Metastasis-Associated Phosphatase Ptp4a3 (PRL-3) Suppresses Murine Colon Cancer

Ptp4a3 (commonly known as PRL-3) is an enigmatic member of the Ptp4a family of prenylated protein tyrosine phosphatases that are highly expressed in many human cancers. Despite strong correlations with tumor metastasis and poor patient prognosis, there is very limited understanding of this gene fami...

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Detalles Bibliográficos
Autores principales: Zimmerman, Mark W., Homanics, Gregg E., Lazo, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610886/
https://www.ncbi.nlm.nih.gov/pubmed/23555575
http://dx.doi.org/10.1371/journal.pone.0058300