Absence of TLR4 Reduces Neurovascular Unit and Secondary Inflammatory Process after Traumatic Brain Injury in Mice

BACKGROUND: Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that contributes to neuronal damage and behavioral impairment. Toll-like receptors (TLRs) are signaling receptors in the innate immune system, although emerging evidence indicates their role in brain injury. We have there...

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Detalles Bibliográficos
Autores principales: Ahmad, Akbar, Crupi, Rosalia, Campolo, Michela, Genovese, Tiziana, Esposito, Emanuela, Cuzzocrea, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610903/
https://www.ncbi.nlm.nih.gov/pubmed/23555560
http://dx.doi.org/10.1371/journal.pone.0057208

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