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Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

Microglial nodules in the normal-appearing white matter have been suggested as the earliest stage(s) of multiple sclerosis (MS) lesion formation. Such nodules are characterized by an absence of leukocyte infiltration, astrogliosis or demyelination, and may develop into active demyelinating MS lesion...

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Detalles Bibliográficos
Autores principales: Singh, Shailender, Metz, Imke, Amor, Sandra, van der Valk, Paul, Stadelmann, Christine, Brück, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611040/
https://www.ncbi.nlm.nih.gov/pubmed/23354834
http://dx.doi.org/10.1007/s00401-013-1082-0

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