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Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons
Microglial nodules in the normal-appearing white matter have been suggested as the earliest stage(s) of multiple sclerosis (MS) lesion formation. Such nodules are characterized by an absence of leukocyte infiltration, astrogliosis or demyelination, and may develop into active demyelinating MS lesion...
Autores principales: | Singh, Shailender, Metz, Imke, Amor, Sandra, van der Valk, Paul, Stadelmann, Christine, Brück, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611040/ https://www.ncbi.nlm.nih.gov/pubmed/23354834 http://dx.doi.org/10.1007/s00401-013-1082-0 |
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