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An inhibitory effect of tumor necrosis factor-alpha antagonist to gene expression in monocrotaline-induced pulmonary hypertensive rats model

PURPOSE: Tumor necrosis factor (TNF)-α is thought to contribute to pulmonary hypertension. We aimed to investigate the effect of infliximab (TNF-α antagonist) treatment on pathologic findings and gene expression in a monocrotaline-induced pulmonary hypertension rat model. METHODS: Six-week-old male...

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Detalles Bibliográficos
Autores principales: Kwon, Jung Hyun, Kim, Kwan Chang, Cho, Min-Sun, Kim, Hae Soon, Sohn, Sejung, Hong, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pediatric Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611045/
https://www.ncbi.nlm.nih.gov/pubmed/23559973
http://dx.doi.org/10.3345/kjp.2013.56.3.116