Pharmaceutical standardization of Mamajjaka (Enicostemma littorale Auct. non Bl) Ghana

Mamajjaka (Enicostemma littorale Auct. non Bl) is a well known folklore medicine frequently used for the treatment of Madhumeha (diabetes mellitus). There is no direct reference available for its antihyperglycaemic activity in Ayurvedic classics. Considering this, a study is planned towards developing pharmaceutical standardization of Mamajjaka Ghana. In this study, five batches of Mamajjaka Ghana were prepared and findings were systematically recorded to maintain the Standard Operating Procedure (SOP). An average of 14.78% Ghana was obtained. The physico-chemical parameters, qualitative test for various functional groups, quantitative estimation of total alkaloids, HPTLC profile, heavy metal analysis and microbial overload were carried out of Mamajjaka Ghana.