Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis

The involvement of the central nervous system (CNS) in familial hemophagocytic lymphohistiocytosis (FHL) has known to be limited to the brain, brain stem, and cerebellum. Herein, we report an 11-year-old boy who presented with neurological symptoms and was diagnosed as FHL by molecular diagnosis. Th...

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Autores principales: Gokce, Muge, Balta, Gunay, Unal, Sule, Oguz, Kader, Cetin, Mualla, Gumruk, Fatma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611908/
https://www.ncbi.nlm.nih.gov/pubmed/23560006
http://dx.doi.org/10.4103/1817-1745.106477
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author Gokce, Muge
Balta, Gunay
Unal, Sule
Oguz, Kader
Cetin, Mualla
Gumruk, Fatma
author_facet Gokce, Muge
Balta, Gunay
Unal, Sule
Oguz, Kader
Cetin, Mualla
Gumruk, Fatma
author_sort Gokce, Muge
collection PubMed
description The involvement of the central nervous system (CNS) in familial hemophagocytic lymphohistiocytosis (FHL) has known to be limited to the brain, brain stem, and cerebellum. Herein, we report an 11-year-old boy who presented with neurological symptoms and was diagnosed as FHL by molecular diagnosis. The hemophagocytic lesions in the CNS were shown to extend to the thoracal level of spinal cord which completely disappeared after the completion of hemophagocytic lymphohistiocytosis-2004 protocol.
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spelling pubmed-36119082013-04-04 Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis Gokce, Muge Balta, Gunay Unal, Sule Oguz, Kader Cetin, Mualla Gumruk, Fatma J Pediatr Neurosci Case Report The involvement of the central nervous system (CNS) in familial hemophagocytic lymphohistiocytosis (FHL) has known to be limited to the brain, brain stem, and cerebellum. Herein, we report an 11-year-old boy who presented with neurological symptoms and was diagnosed as FHL by molecular diagnosis. The hemophagocytic lesions in the CNS were shown to extend to the thoracal level of spinal cord which completely disappeared after the completion of hemophagocytic lymphohistiocytosis-2004 protocol. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3611908/ /pubmed/23560006 http://dx.doi.org/10.4103/1817-1745.106477 Text en Copyright: © Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gokce, Muge
Balta, Gunay
Unal, Sule
Oguz, Kader
Cetin, Mualla
Gumruk, Fatma
Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
title Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
title_full Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
title_fullStr Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
title_full_unstemmed Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
title_short Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
title_sort spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611908/
https://www.ncbi.nlm.nih.gov/pubmed/23560006
http://dx.doi.org/10.4103/1817-1745.106477
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