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Altered protein conformation and lower stability of the dystrophic transforming growth factor beta-induced protein mutants

PURPOSE: Transforming growth factor beta-induced protein (TGFBIp) is a widely expressed extracellular matrix protein that plays roles in cell adhesion and migration, differentiation, apoptosis, bone morphogenesis, and carcinogenesis. Mutations of TGFBIp have been linked to stromal corneal dystrophie...

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Detalles Bibliográficos
Autores principales: Grothe, Heather L., Little, Morgan R., Sjogren, Phayvanh P., Chang, Angela A., Nelson, Elizabeth F., Yuan, Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611947/
https://www.ncbi.nlm.nih.gov/pubmed/23559853