Cargando…

Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis

BACKGROUND: Vascular endothelial cells (ECs) express and release protein components of the complement pathways, as well as secreting and anchoring ultra-large von Willebrand factor (ULVWF) multimers in long string-like structures that initiate platelet adhesion during hemostasis and thrombosis. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Turner, Nancy A., Moake, Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612042/ https://www.ncbi.nlm.nih.gov/pubmed/23555663 http://dx.doi.org/10.1371/journal.pone.0059372

Ejemplares similares

Complement Component C3 Binds to the A3 Domain of von Willebrand Factor
por: Nolasco, Jennifer G., et al.
Publicado: (2018)

Heat-inactivated Factor B inhibits alternative pathway fluid-phase activation and convertase formation on endothelial cell-secreted ultra-large von Willebrand factor strings
por: Turner, Nancy A., et al.
Publicado: (2023)

Porcine and Canine von Willebrand Factor and von Willebrand Disease: Hemostasis, Thrombosis, and Atherosclerosis Studies
por: Nichols, Timothy C., et al.
Publicado: (2010)

Regulatory Components of the Alternative Complement Pathway in Endothelial Cell Cytoplasm, Factor H and Factor I, Are Not Packaged in Weibel-Palade Bodies
por: Turner, Nancy A., et al.
Publicado: (2015)

von Willebrand factor links primary hemostasis to innate immunity
por: Drakeford, Clive, et al.
Publicado: (2022)

Complement component 5 promotes lethal thrombosis
por: Mizuno, Tomohiro, et al.
Publicado: (2017)

Deficiency of complement factor H-related proteins and autoantibody-positive hemolytic uremic syndrome in an infant with combined partial deficiencies and autoantibodies to complement factor H and ADAMTS13
por: Michael, Mini, et al.
Publicado: (2018)

Deficiency of complement factor H-related proteins and autoantibody-positive hemolytic uremic syndrome in an infant with combined partial deficiencies and autoantibodies to complement factor H and ADAMTS13
por: Michael, Mini, et al.
Publicado: (2018)

Associations between the von Willebrand Factor—ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality
por: Sinkovits, György, et al.
Publicado: (2022)

Complement C1q Enhances Primary Hemostasis
por: Donat, Claudia, et al.
Publicado: (2020)

von Willebrand Factor, Free Hemoglobin and Thrombosis in ECMO
por: Valladolid, Christian, et al.
Publicado: (2018)

Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis
por: Stockschlaeder, Marcus, et al.
Publicado: (2014)

Effects of Increased Von Willebrand Factor Levels on Primary Hemostasis in Thrombocytopenic Patients with Liver Cirrhosis
por: Wannhoff, Andreas, et al.
Publicado: (2014)

Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytes
Publicado: (1980)

Von Willebrand Factor Activity in Thrombosis: An Overlooked Target for Intervention?
por: Shalmi, Theodor W., et al.
Publicado: (2021)

Substitutions at position 263 within the von Willebrand factor type A domain determine the functionality of complement C2 protein
por: Kuźniewska, Alicja, et al.
Publicado: (2022)

Assembly Mechanism of Mucin and von Willebrand Factor Polymers
por: Javitt, Gabriel, et al.
Publicado: (2020)

Hemophilia and von Willebrand disease: Factor VIII and von Willebrand factor
por: Sharma, Prashant
Publicado: (2019)

von Willebrand Factor is elevated in HIV patients with a history of thrombosis
por: van den Dries, Lennert W. J., et al.
Publicado: (2015)

Binding of von Willebrand Factor to Complement C1q Decreases the Phagocytosis of Cholesterol Crystals and Subsequent IL-1 Secretion in Macrophages
por: Donat, Claudia, et al.
Publicado: (2019)

Alternative Complement Activity in the Egg Cytosol of Amphioxus Branchiostoma belcheri: Evidence for the Defense Role of Maternal Complement Components
por: Liang, Yujun, et al.
Publicado: (2009)

Complement 1 Inhibitor Is a Regulator of the Alternative Complement Pathway
por: Jiang, Haixiang, et al.
Publicado: (2001)

Diagnostic Value of Measuring Platelet Von Willebrand Factor in Von Willebrand Disease
por: Casonato, Alessandra, et al.
Publicado: (2016)

DEFICIENCY OF THE FIFTH COMPONENT OF COMPLEMENT IN MICE WITH AN INHERITED COMPLEMENT DEFECT
por: Nilsson, Ulf R., et al.
Publicado: (1967)

DEFICIENCY OF THE SIXTH COMPONENT OF COMPLEMENT IN RABBITS WITH AN INHERITED COMPLEMENT DEFECT
por: Rother, Klaus, et al.
Publicado: (1966)

Complement in Hemolysis- and Thrombosis- Related Diseases
por: Luo, Shanshan, et al.
Publicado: (2020)

A genetically-engineered von Willebrand disease type 2B mouse model displays defects in hemostasis and inflammation
por: Adam, Frédéric, et al.
Publicado: (2016)

Essential Thrombocythemia and Acquired von Willebrand Syndrome: The Shadowlands between Thrombosis and Bleeding
por: Awada, Hassan, et al.
Publicado: (2020)

COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles
por: Becker, Richard C., et al.
Publicado: (2021)

The Role of Von Willebrand Factor in the Pathogenesis of Pulmonary Vascular Thrombosis in COVID-19
por: Babkina, Anastasiya S., et al.
Publicado: (2022)

Changes of von Willebrand Factor during Pregnancy in Women with and without von Willebrand Disease
por: Castaman, Giancarlo
Publicado: (2013)

Genetic Variation in the von Willebrand Factor Gene in Swedish von Willebrand Disease Patients
por: Manderstedt, Eric, et al.
Publicado: (2018)

The alternative complement pathway revisited
por: Harboe, Morten, et al.
Publicado: (2008)

Endothelial Function in Patients With Von Willebrand Disease
por: Noone, Stephanie, et al.
Publicado: (2021)

Von Willebrand Disease: An Overview
por: Bharati, K. Pavani, et al.
Publicado: (2011)

On the Versatility of von Willebrand Factor
por: Rauch, Antoine, et al.
Publicado: (2013)

Of von Willebrand factor and platelets
por: Bryckaert, Marijke, et al.
Publicado: (2014)

Cerebral Sinus and Venous Thrombosis Associated with von Willebrand Factor, Independently of Factor VIII
por: Terashima, Mari, et al.
Publicado: (2008)

Von Willebrand factor in the plasma and in the tumor tissue predicts cancer-associated thrombosis and mortality
por: Karampinis, Ioannis, et al.
Publicado: (2022)

Classification of von Willebrand disease in the context of modern contemporary von Willebrand factor testing methodologies
por: Favaloro, Emmanuel J.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vdss048fdoamq3br510plqe3u8