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Whole Genome Sequence Analysis of the First Australian OXA-48-Producing Outbreak-Associated Klebsiella pneumoniae Isolates: The Resistome and In Vivo Evolution

Whole genome sequencing was used to characterize the resistome of intensive care unit (ICU) outbreak-associated carbapenem-resistant K. pneumoniae isolates. Importantly, and of particular concern, the carbapenem-hydrolyzing β-lactamase gene bla (OXA-48) and the extended-spectrum β-lactamase gene bla...

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Detalles Bibliográficos
Autores principales:	Espedido, Björn A., Steen, Jason A., Ziochos, Helen, Grimmond, Sean M., Cooper, Matthew A., Gosbell, Iain B., van Hal, Sebastiaan J., Jensen, Slade O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612081/ https://www.ncbi.nlm.nih.gov/pubmed/23555831 http://dx.doi.org/10.1371/journal.pone.0059920

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