Cargando…

Quantitative determination of imatinib stability under various stress conditions

OBJECTIVE: A simple, rapid, reverse phase and stability-indicating high-performance liquid chromatography (HPLC) method for the estimation of imatinib in solution and in plasma under forced degradation conditions was developed. MATERIALS AND METHODS: The method employed isocratic elution using a Wat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alkharfy, Khalid Mohammed, Khan, Rao Muzaffer Ali, Al-Asmari, Majed, Alhadeyah, Baderelddin Hashim, Ahmad, Ajaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612339/ https://www.ncbi.nlm.nih.gov/pubmed/23559824 http://dx.doi.org/10.4103/0975-7406.106570

Ejemplares similares

The potential role of thymoquinone in preventing the cardiovascular complications of COVID-19
por: Ahmad, Ajaz, et al.
Publicado: (2021)

Saudi Arabia, pharmacists and COVID-19 pandemic
por: Ahmad, Ajaz, et al.
Publicado: (2020)

Thymoquinone modulates the expression of sepsis-related microRNAs in a CLP model
por: Alkharfy, Khalid M., et al.
Publicado: (2022)

Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation and in silico modeling in male and female rats
por: Ahmad, Ajaz, et al.
Publicado: (2020)

Herb-drug interaction: Effect of sinapic acid on the pharmacokinetics of dasatinib in rats
por: Shahid, Mudassar, et al.
Publicado: (2023)

Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible food drug interaction
por: Raish, Mohammad, et al.
Publicado: (2018)

Molecular Mobility and Stability Studies of Amorphous Imatinib Mesylate
por: Karolewicz, Bożena, et al.
Publicado: (2019)

Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model
por: Ahmad, Ajaz, et al.
Publicado: (2019)

Structural Refolding and Thermal Stability of Myoglobin in the Presence of Mixture of Crowders: Importance of Various Interactions for Protein Stabilization in Crowded Conditions
por: Parray, Zahoor Ahmad, et al.
Publicado: (2021)

Sinapic Acid Ameliorates Oxidative Stress, Inflammation, and Apoptosis in Acute Doxorubicin-Induced Cardiotoxicity via the NF-κB-Mediated Pathway
por: Bin Jardan, Yousef A., et al.
Publicado: (2020)

Myricetin (3,3′,4′,5,5′,7-Hexahydroxyflavone) Prevents 5-Fluorouracil-Induced Cardiotoxicity
por: Arafah, Azher, et al.
Publicado: (2022)

Quality assessment of different brands of atorvastatin tablets available in Riyadh, Saudi Arabia
por: AlMuhsin, Ali, et al.
Publicado: (2022)

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose
por: Roosendaal, Jeroen, et al.
Publicado: (2020)

Hepatoprotective activity of Lepidium sativum seeds against D-galactosamine/lipopolysaccharide induced hepatotoxicity in animal model
por: Raish, Mohammad, et al.
Publicado: (2016)

Increased IL-4 mRNA expression and poly-aromatic hydrocarbon concentrations from children with asthma
por: Al-Daghri, Nasser M, et al.
Publicado: (2014)

Influence of Overt Diabetes Mellitus on Cyclosporine Pharmacokinetics in a Canine Model
por: Alkharfy, Khalid M.
Publicado: (2009)

Food Advertisements: To Ban or Not to Ban?
por: Alkharfy, Khalid M.
Publicado: (2011)

The pharmacogenetics of imatinib
por: Dulucq, Stéphanie, et al.
Publicado: (2010)

Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role
por: Raish, Mohammad, et al.
Publicado: (2021)

Sinapic Acid Ameliorates Acetic Acid-Induced Ulcerative Colitis in Rats by Suppressing Inflammation, Oxidative Stress, and Apoptosis
por: Shahid, Mudassar, et al.
Publicado: (2022)

Primary imatinib failure rescued by dasatinib and maintained by reintroduction of imatinib
por: Kumar, Rajiv, et al.
Publicado: (2017)

Renal tuberculosis in an imatinib-treated chronic myeloid leukemia
por: Chandra, Abhilash, et al.
Publicado: (2020)

Optimization of the extraction condition for benzyl isothiocyanate contents in Salvadora persica roots “Siwak”
por: Abdel-Kader, Maged S., et al.
Publicado: (2019)

Stability of Methylphenidate under Various pH Conditions in the Presence or Absence of Gut Microbiota
por: Aresti-Sanz, Julia, et al.
Publicado: (2021)

Stability of Metronidazole and Its Complexes with Silver(I) Salts under Various Stress Conditions
por: Starek, Małgorzata, et al.
Publicado: (2021)

The Stability of the Anti-Müllerian Hormone in Serum and Plasma Samples under Various Preanalytical Conditions
por: Vrzáková, Radana, et al.
Publicado: (2023)

Behavior of protein-polysaccharide conjugate-stabilized food emulsions under various destabilization conditions
por: Nooshkam, Majid, et al.
Publicado: (2023)

Reliability of implant stability measuring devices depending on various clinical conditions: an in vitro study
por: Lee, Han-Na, et al.
Publicado: (2023)

Exploiting the promiscuity of imatinib
por: Lee, Shun J, et al.
Publicado: (2009)

Imatinib-induced pancreatitis
por: Varma, Mahesh R., et al.
Publicado: (2010)

Reintroduction of Imatinib in GIST
por: Reid, T.
Publicado: (2013)

Imatinib Use in Pregnancy
por: Webb, Michael J, et al.
Publicado: (2012)

Imatinib-Induced Psoriasis
por: Atalay, Figen, et al.
Publicado: (2013)

The Side Effects of Imatinib
por: Uzer, Elmas, et al.
Publicado: (2013)

Imatinib-induced Gynecomastia
por: Gupta, Pragya, et al.
Publicado: (2019)

Selected Dietary Nutrients and the Prevalence of Metabolic Syndrome in Adult Males and Females in Saudi Arabia: A Pilot Study
por: Al-Daghri, Nasser M., et al.
Publicado: (2013)

Quantitative assessment of Ki67 expression in correlation with various breast cancer characteristics and survival rate; cross sectional study
por: Mohammed, Ayad Ahmad
Publicado: (2019)

The Effect of Apigenin on Pharmacokinetics of Imatinib and Its Metabolite N-Desmethyl Imatinib in Rats
por: Liu, Xian-yun, et al.
Publicado: (2013)

Sensitive Detection of Pre-Existing BCR-ABL Kinase Domain Mutations in CD34+ Cells of Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia Patients Is Associated with Imatinib Resistance: Implications in the Post-Imatinib Era
por: Iqbal, Zafar, et al.
Publicado: (2013)

Thiamine and its phosphate esters in relation to cardiometabolic risk factors in Saudi Arabs
por: Al-Daghri, Nasser M, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_mo19rq7mom0dmu7gr736ppncto