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Structural visualization of key steps in human transcription initiation

Eukaryotic transcription initiation requires the assembly of general transcription factors into a pre-initiation complex that ensures the accurate loading of RNA polymerase II at the transcription start site. The molecular mechanism and function of this assembly have remained elusive due to lack of...

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Detalles Bibliográficos
Autores principales: He, Yuan, Fang, Jie, Taatjes, Dylan J., Nogales, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612373/
https://www.ncbi.nlm.nih.gov/pubmed/23446344
http://dx.doi.org/10.1038/nature11991

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