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Co-amoxiclav-induced Stevens Johnson Syndrome in a child
Stevens-Johnson Syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson Syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612873/ https://www.ncbi.nlm.nih.gov/pubmed/23560121 http://dx.doi.org/10.11604/pamj.2013.14.38.1408 |
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author | Fathallah, Neila Hanen, Zayani Slim, Raoudha Boussofara, Lobna Najet, Ghariani Bouraoui, Kamel Salem, Chaker Ben |
author_facet | Fathallah, Neila Hanen, Zayani Slim, Raoudha Boussofara, Lobna Najet, Ghariani Bouraoui, Kamel Salem, Chaker Ben |
author_sort | Fathallah, Neila |
collection | PubMed |
description | Stevens-Johnson Syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson Syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome in children. Herein, we report a co-amoxiclav-induced Stevens-Johnson Syndrome occurring in an 18-month-old child. The diagnosis of SJS is often challenging in children and other possible diseases should be ruled out. The etiology of this syndrome is not yet fully understood. It is thought to be mediated by an immunologic mechanism. Management involves early identification, withdrawal of the culprit drug and rapid initiation of supportive therapies. |
format | Online Article Text |
id | pubmed-3612873 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-36128732013-04-04 Co-amoxiclav-induced Stevens Johnson Syndrome in a child Fathallah, Neila Hanen, Zayani Slim, Raoudha Boussofara, Lobna Najet, Ghariani Bouraoui, Kamel Salem, Chaker Ben Pan Afr Med J Case Report Stevens-Johnson Syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson Syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome in children. Herein, we report a co-amoxiclav-induced Stevens-Johnson Syndrome occurring in an 18-month-old child. The diagnosis of SJS is often challenging in children and other possible diseases should be ruled out. The etiology of this syndrome is not yet fully understood. It is thought to be mediated by an immunologic mechanism. Management involves early identification, withdrawal of the culprit drug and rapid initiation of supportive therapies. The African Field Epidemiology Network 2013-01-27 /pmc/articles/PMC3612873/ /pubmed/23560121 http://dx.doi.org/10.11604/pamj.2013.14.38.1408 Text en © Neila Fathallah et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Fathallah, Neila Hanen, Zayani Slim, Raoudha Boussofara, Lobna Najet, Ghariani Bouraoui, Kamel Salem, Chaker Ben Co-amoxiclav-induced Stevens Johnson Syndrome in a child |
title | Co-amoxiclav-induced Stevens Johnson Syndrome in a child |
title_full | Co-amoxiclav-induced Stevens Johnson Syndrome in a child |
title_fullStr | Co-amoxiclav-induced Stevens Johnson Syndrome in a child |
title_full_unstemmed | Co-amoxiclav-induced Stevens Johnson Syndrome in a child |
title_short | Co-amoxiclav-induced Stevens Johnson Syndrome in a child |
title_sort | co-amoxiclav-induced stevens johnson syndrome in a child |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612873/ https://www.ncbi.nlm.nih.gov/pubmed/23560121 http://dx.doi.org/10.11604/pamj.2013.14.38.1408 |
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