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Co-amoxiclav-induced Stevens Johnson Syndrome in a child

Stevens-Johnson Syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson Syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome...

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Autores principales: Fathallah, Neila, Hanen, Zayani, Slim, Raoudha, Boussofara, Lobna, Najet, Ghariani, Bouraoui, Kamel, Salem, Chaker Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612873/
https://www.ncbi.nlm.nih.gov/pubmed/23560121
http://dx.doi.org/10.11604/pamj.2013.14.38.1408
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author Fathallah, Neila
Hanen, Zayani
Slim, Raoudha
Boussofara, Lobna
Najet, Ghariani
Bouraoui, Kamel
Salem, Chaker Ben
author_facet Fathallah, Neila
Hanen, Zayani
Slim, Raoudha
Boussofara, Lobna
Najet, Ghariani
Bouraoui, Kamel
Salem, Chaker Ben
author_sort Fathallah, Neila
collection PubMed
description Stevens-Johnson Syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson Syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome in children. Herein, we report a co-amoxiclav-induced Stevens-Johnson Syndrome occurring in an 18-month-old child. The diagnosis of SJS is often challenging in children and other possible diseases should be ruled out. The etiology of this syndrome is not yet fully understood. It is thought to be mediated by an immunologic mechanism. Management involves early identification, withdrawal of the culprit drug and rapid initiation of supportive therapies.
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spelling pubmed-36128732013-04-04 Co-amoxiclav-induced Stevens Johnson Syndrome in a child Fathallah, Neila Hanen, Zayani Slim, Raoudha Boussofara, Lobna Najet, Ghariani Bouraoui, Kamel Salem, Chaker Ben Pan Afr Med J Case Report Stevens-Johnson Syndrome is an uncommon life threatening disease generally induced by drugs. Antibiotics, mainly sulphonamides, are the most involved drugs in Stevens-Johnson Syndrome in children. Co-amoxiclav is a well tolerated antibiotic. It has never been reported to cause, lonely this syndrome in children. Herein, we report a co-amoxiclav-induced Stevens-Johnson Syndrome occurring in an 18-month-old child. The diagnosis of SJS is often challenging in children and other possible diseases should be ruled out. The etiology of this syndrome is not yet fully understood. It is thought to be mediated by an immunologic mechanism. Management involves early identification, withdrawal of the culprit drug and rapid initiation of supportive therapies. The African Field Epidemiology Network 2013-01-27 /pmc/articles/PMC3612873/ /pubmed/23560121 http://dx.doi.org/10.11604/pamj.2013.14.38.1408 Text en © Neila Fathallah et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fathallah, Neila
Hanen, Zayani
Slim, Raoudha
Boussofara, Lobna
Najet, Ghariani
Bouraoui, Kamel
Salem, Chaker Ben
Co-amoxiclav-induced Stevens Johnson Syndrome in a child
title Co-amoxiclav-induced Stevens Johnson Syndrome in a child
title_full Co-amoxiclav-induced Stevens Johnson Syndrome in a child
title_fullStr Co-amoxiclav-induced Stevens Johnson Syndrome in a child
title_full_unstemmed Co-amoxiclav-induced Stevens Johnson Syndrome in a child
title_short Co-amoxiclav-induced Stevens Johnson Syndrome in a child
title_sort co-amoxiclav-induced stevens johnson syndrome in a child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612873/
https://www.ncbi.nlm.nih.gov/pubmed/23560121
http://dx.doi.org/10.11604/pamj.2013.14.38.1408
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