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CXCR1/CXCR2 Antagonism Is Effective in Pulmonary Defense against Klebsiella pneumoniae Infection

Klebsiella pneumoniae-associated pathology is largely mediated by neutrophilic inflammation. In this study, we administered Klebsiella pneumoniae to experimental guinea pig groups and the ELR-CXC chemokine antagonist CXCL8((3–72)), ceftazidime, and dexamethasone to different groups, respectively. Af...

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Detalles Bibliográficos
Autores principales:	Wei, Jing, Peng, Jing, Wang, Bing, Qu, Hong, Wang, Shiyi, Faisal, Aziz, Cheng, Jia-Wei, Gordon, John R., Li, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613076/ https://www.ncbi.nlm.nih.gov/pubmed/23586055 http://dx.doi.org/10.1155/2013/720975

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