Colloidal Aggregation Causes Inhibition of G Protein-Coupled Receptors

[Image: see text] Colloidal aggregation is the dominant mechanism for artifactual inhibition of soluble proteins, and controls against it are now widely deployed. Conversely, investigating this mechanism for membrane-bound receptors has proven difficult. Here we investigate the activity of four well...

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Detalles Bibliográficos
Autores principales: Sassano, Maria F., Doak, Allison K., Roth, Bryan L., Shoichet, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613083/
https://www.ncbi.nlm.nih.gov/pubmed/23437772
http://dx.doi.org/10.1021/jm301749y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613083/
https://www.ncbi.nlm.nih.gov/pubmed/23437772
http://dx.doi.org/10.1021/jm301749y

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