Cargando…

Positional editing of transmembrane domains during ion channel assembly

The integration of transmembrane (TM)-spanning regions of many channels and ion transporters is potentially compromised by the presence of polar and charged residues required for biological function. Although the two TMs of the ATP-gated ion channel subunit P2X2 each contain charged/polar amino acid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Öjemalm, Karin, Watson, Helen R., Roboti, Peristera, Cross, Benedict C. S., Warwicker, Jim, von Heijne, Gunnar, High, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613178/ https://www.ncbi.nlm.nih.gov/pubmed/23230148 http://dx.doi.org/10.1242/jcs.111773

Ejemplares similares

Mitochondrial antiviral-signalling protein is a client of the BAG6 protein quality control complex
por: Roboti, Peristera, et al.
Publicado: (2022)

OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation
por: Dumax-Vorzet, Audrey, et al.
Publicado: (2013)

Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex
por: Watson, Helen R., et al.
Publicado: (2013)

Computational Tools for Interpreting Ion Channel pH-Dependence
por: Sazanavets, Ivan, et al.
Publicado: (2015)

Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis
por: Roboti, Peristera, et al.
Publicado: (2021)

Formation of Transmembrane Helices In Vivo—Is Hydrophobicity All that Matters?
por: von Heijne, Gunnar
Publicado: (2007)

His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation
por: Parkinson, Gabrielle, et al.
Publicado: (2021)

The golgin GMAP-210 is required for efficient membrane trafficking in the early secretory pathway
por: Roboti, Peristera, et al.
Publicado: (2015)

Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
por: O’Keefe, Sarah, et al.
Publicado: (2021)

Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor
por: O'Keefe, Sarah, et al.
Publicado: (2021)

A biochemical analysis of the constraints of tail-anchored protein biogenesis
por: Leznicki, Pawel, et al.
Publicado: (2011)

Assembling the Transmembrane Domain of Vpu from HIV-1
por: Fischer, Wolfgang B., et al.
Publicado: (2012)

Biological insertion of computationally designed short transmembrane segments
por: Baeza-Delgado, Carlos, et al.
Publicado: (2016)

Pentameric ligand-gated ion channels exhibit distinct transmembrane domain archetypes for folding/expression and function
por: Therien, J. P. Daniel, et al.
Publicado: (2017)

MERS coronavirus envelope protein has a single transmembrane domain that forms pentameric ion channels
por: Surya, Wahyu, et al.
Publicado: (2015)

Structure of mechanically activated ion channel OSCA2.3 reveals mobile elements in the transmembrane domain
por: Jojoa-Cruz, Sebastian, et al.
Publicado: (2023)

Coupling of vesicle tethering and Rab binding is required for in vivo functionality of the golgin GMAP-210
por: Sato, Keisuke, et al.
Publicado: (2015)

Hydrophobic Blocks Facilitate Lipid Compatibility and Translocon Recognition of Transmembrane Protein Sequences
por: Stone, Tracy A., et al.
Publicado: (2015)

Swapping of transmembrane domains in the epithelial calcium channel TRPV6
por: Singh, Appu K., et al.
Publicado: (2017)

Elevation of Proteasomal Substrate Levels Sensitizes Cells to Apoptosis Induced by Inhibition of Proteasomal Deubiquitinases
por: Sun, Chao, et al.
Publicado: (2014)

Predicting the Assembly of the Transmembrane Domains of Viral Channel Forming Proteins and Peptide Drug Screening Using a Docking Approach
por: Huang, Ta-Chou, et al.
Publicado: (2022)

P2Y(1) receptor modulation of endogenous ion channel function in Xenopus oocytes: Involvement of transmembrane domains
por: Lee, So Yeong, et al.
Publicado: (2004)

Confined Dynamics of Water in Transmembrane Pore of TRPV1 Ion Channel
por: Trofimov, Yury A., et al.
Publicado: (2019)

Domain–domain interactions in ion channels
por: Zheng, Jie
Publicado: (2013)

Pore-forming transmembrane domains control ion selectivity and selectivity filter conformation in the KirBac1.1 potassium channel
por: Matamoros, Marcos, et al.
Publicado: (2021)

SPONTANEOUS TRANSMEMBRANE HELIX INSERTION THERMODYNAMICALLY MIMICS TRANSLOCON-GUIDED INSERTION
por: Ulmschneider, Martin B., et al.
Publicado: (2014)

Charged residues next to transmembrane regions revisited: “Positive-inside rule” is complemented by the “negative inside depletion/outside enrichment rule”
por: Baker, James Alexander, et al.
Publicado: (2017)

Perspectives on Ion Channel Assembly
por: Andersen, Olaf Sparre
Publicado: (1999)

Mechanism of influenza A M2 transmembrane domain assembly in lipid membranes
por: Georgieva, Elka R., et al.
Publicado: (2015)

Ion access pathway to the transmembrane pore in P2X receptor channels
por: Kawate, Toshimitsu, et al.
Publicado: (2011)

Transmembrane Protein 175, a Lysosomal Ion Channel Related to Parkinson’s Disease
por: Tang, Tuoxian, et al.
Publicado: (2023)

Editorial: “Small molecules targeting transmembrane receptors and ion channels in drug discovery”
por: Vitale, Rosa Maria, et al.
Publicado: (2023)

Erratum to: Charged residues next to transmembrane regions revisited: “Positive-inside rule” is complemented by the “negative inside depletion/outside enrichment rule”
por: Baker, James Alexander, et al.
Publicado: (2017)

Energetic Calculations to Decipher pH-Dependent Oligomerization and Domain Swapping of Proteins
por: Shingate, Prashant, et al.
Publicado: (2015)

Interaction of the Aromatics Tyr-72/Trp-288 in the Interface of the Extracellular and Transmembrane Domains Is Essential for Proton Gating of Acid-sensing Ion Channels
por: Li, Tianbo, et al.
Publicado: (2009)

Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation
por: Schwarz, Nicole, et al.
Publicado: (2012)

Multi-Ion Mechanism for Ion Permeation and Block in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
por: Linsdell, Paul, et al.
Publicado: (1997)

TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane
por: Botelho, Salomé Calado, et al.
Publicado: (2011)

Transmembrane but not soluble helices fold inside the ribosome tunnel
por: Bañó-Polo, Manuel, et al.
Publicado: (2018)

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains
por: Wang, Jing Yang (John), et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5of36bmg2knm146c9d7ai5a9gh