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Intralesional corticosteroid injections in the treatment of central giant cell lesions of the jaws: A meta-analytic study
Objective: The aim of this study was to evaluate the response of treatment of central giant cell lesion to intralesional corticosteroid injections. Study Design: Review of articles indexed in PubMed on the topic between the years 1988 and 2011, and development of a descriptive meta-analysis of the r...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613330/ https://www.ncbi.nlm.nih.gov/pubmed/23385503 http://dx.doi.org/10.4317/medoral.18345 |
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author | Osterne, Rafael L. Araújo, Phelype M. de Souza-Carvalho, Abrahao C. Cavalcante, Roberta B. Sant’Ana, Eduardo Nongueira, Renato L. |
author_facet | Osterne, Rafael L. Araújo, Phelype M. de Souza-Carvalho, Abrahao C. Cavalcante, Roberta B. Sant’Ana, Eduardo Nongueira, Renato L. |
author_sort | Osterne, Rafael L. |
collection | PubMed |
description | Objective: The aim of this study was to evaluate the response of treatment of central giant cell lesion to intralesional corticosteroid injections. Study Design: Review of articles indexed in PubMed on the topic between the years 1988 and 2011, and development of a descriptive meta-analysis of the results. Results: Sample of 41 patients primarily treated with intralesional corticosteroid injections was obtained, with a male female ratio of 1:0.95, being 23 aggressive and 18 non-aggressive central giant cell lesions. Triamcinolone acetonide and triamcinolone hexacetonide were the drugs used, and 78.0% cases were considered as good result, 14.6% were considered as moderate response and 7.3% were considered as negative result to treatment. Considering the aggressiveness, 88.9% of non-aggressive lesions presented a good response to treatment, in aggressive central giant cell lesions, 69.6% presented a good response to intralesional corticosteroid injections. Conclusion: In view of the results analyzed, intralesional corticosteroid injections could be considered as first treatment option for central giant cell lesion. Key words:Central giant cell lesion, corticosteroids injections, triamcinolone hexacetonide, triamcinolone acetonide. |
format | Online Article Text |
id | pubmed-3613330 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-36133302013-04-02 Intralesional corticosteroid injections in the treatment of central giant cell lesions of the jaws: A meta-analytic study Osterne, Rafael L. Araújo, Phelype M. de Souza-Carvalho, Abrahao C. Cavalcante, Roberta B. Sant’Ana, Eduardo Nongueira, Renato L. Med Oral Patol Oral Cir Bucal Review-Article Objective: The aim of this study was to evaluate the response of treatment of central giant cell lesion to intralesional corticosteroid injections. Study Design: Review of articles indexed in PubMed on the topic between the years 1988 and 2011, and development of a descriptive meta-analysis of the results. Results: Sample of 41 patients primarily treated with intralesional corticosteroid injections was obtained, with a male female ratio of 1:0.95, being 23 aggressive and 18 non-aggressive central giant cell lesions. Triamcinolone acetonide and triamcinolone hexacetonide were the drugs used, and 78.0% cases were considered as good result, 14.6% were considered as moderate response and 7.3% were considered as negative result to treatment. Considering the aggressiveness, 88.9% of non-aggressive lesions presented a good response to treatment, in aggressive central giant cell lesions, 69.6% presented a good response to intralesional corticosteroid injections. Conclusion: In view of the results analyzed, intralesional corticosteroid injections could be considered as first treatment option for central giant cell lesion. Key words:Central giant cell lesion, corticosteroids injections, triamcinolone hexacetonide, triamcinolone acetonide. Medicina Oral S.L. 2013-03 2013-02-05 /pmc/articles/PMC3613330/ /pubmed/23385503 http://dx.doi.org/10.4317/medoral.18345 Text en Copyright: © 2013 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review-Article Osterne, Rafael L. Araújo, Phelype M. de Souza-Carvalho, Abrahao C. Cavalcante, Roberta B. Sant’Ana, Eduardo Nongueira, Renato L. Intralesional corticosteroid injections in the treatment of central giant cell lesions of the jaws: A meta-analytic study |
title | Intralesional corticosteroid injections in the treatment of central
giant cell lesions of the jaws: A meta-analytic study |
title_full | Intralesional corticosteroid injections in the treatment of central
giant cell lesions of the jaws: A meta-analytic study |
title_fullStr | Intralesional corticosteroid injections in the treatment of central
giant cell lesions of the jaws: A meta-analytic study |
title_full_unstemmed | Intralesional corticosteroid injections in the treatment of central
giant cell lesions of the jaws: A meta-analytic study |
title_short | Intralesional corticosteroid injections in the treatment of central
giant cell lesions of the jaws: A meta-analytic study |
title_sort | intralesional corticosteroid injections in the treatment of central
giant cell lesions of the jaws: a meta-analytic study |
topic | Review-Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613330/ https://www.ncbi.nlm.nih.gov/pubmed/23385503 http://dx.doi.org/10.4317/medoral.18345 |
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