CLL Cells Respond to B-Cell Receptor Stimulation with a MicroRNA/mRNA Signature Associated with MYC Activation and Cell Cycle Progression

Chronic lymphocytic leukemia (CLL) is a disease with variable clinical outcome. Several prognostic factors such as the immunoglobulin heavy chain variable genes (IGHV) mutation status are linked to the B-cell receptor (BCR) complex, supporting a role for triggering the BCR in vivo in the pathogenesi...

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Detalles Bibliográficos
Autores principales: Pede, Valerie, Rombout, Ans, Vermeire, Jolien, Naessens, Evelien, Mestdagh, Pieter, Robberecht, Nore, Vanderstraeten, Hanne, Van Roy, Nadine, Vandesompele, Jo, Speleman, Frank, Philippé, Jan, Verhasselt, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613353/
https://www.ncbi.nlm.nih.gov/pubmed/23560086
http://dx.doi.org/10.1371/journal.pone.0060275

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