Leukemia Mediated Endothelial Cell Activation Modulates Leukemia Cell Susceptibility to Chemotherapy through a Positive Feedback Loop Mechanism

In acute myeloid leukemia (AML), the chances of achieving disease-free survival are low. Studies have demonstrated a supportive role of endothelial cells (ECs) in normal hematopoiesis. Here we show that similar intercellular relationships exist in leukemia. We demonstrate that leukemia cells themsel...

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Detalles Bibliográficos
Autores principales: Pezeshkian, Bahareh, Donnelly, Christopher, Tamburo, Kelley, Geddes, Timothy, Madlambayan, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613371/
https://www.ncbi.nlm.nih.gov/pubmed/23560111
http://dx.doi.org/10.1371/journal.pone.0060823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613371/
https://www.ncbi.nlm.nih.gov/pubmed/23560111
http://dx.doi.org/10.1371/journal.pone.0060823

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