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Leukemia Mediated Endothelial Cell Activation Modulates Leukemia Cell Susceptibility to Chemotherapy through a Positive Feedback Loop Mechanism

In acute myeloid leukemia (AML), the chances of achieving disease-free survival are low. Studies have demonstrated a supportive role of endothelial cells (ECs) in normal hematopoiesis. Here we show that similar intercellular relationships exist in leukemia. We demonstrate that leukemia cells themsel...

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Detalles Bibliográficos
Autores principales:	Pezeshkian, Bahareh, Donnelly, Christopher, Tamburo, Kelley, Geddes, Timothy, Madlambayan, Gerard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613371/ https://www.ncbi.nlm.nih.gov/pubmed/23560111 http://dx.doi.org/10.1371/journal.pone.0060823

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