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The scaffold protein EPG-7 links cargo–receptor complexes with the autophagic assembly machinery

The mechanism by which protein aggregates are selectively degraded by autophagy is poorly understood. Previous studies show that a family of Atg8-interacting proteins function as receptors linking specific cargoes to the autophagic machinery. Here we demonstrate that during Caenorhabditis elegans em...

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Detalles Bibliográficos
Autores principales: Lin, Long, Yang, Peiguo, Huang, Xinxin, Zhang, Hui, Lu, Qun, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613692/
https://www.ncbi.nlm.nih.gov/pubmed/23530068
http://dx.doi.org/10.1083/jcb.201209098

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