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The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3
Membrane microcompartments of the early endosomes serve as a sorting and signaling platform, where receptors are either recycled back to the plasma membrane or forwarded to the lysosome for destruction. In metazoan cells, three complexes, termed BLOC-1 to -3, mediate protein sorting from the early e...
Autores principales: | John Peter, Arun T., Lachmann, Jens, Rana, Meenakshi, Bunge, Madeleine, Cabrera, Margarita, Ungermann, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613695/ https://www.ncbi.nlm.nih.gov/pubmed/23547030 http://dx.doi.org/10.1083/jcb.201210038 |
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