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A germline variant N375S in MET and gastric cancer susceptibility in a Chinese population

MET tyrosine kinase and its ligand, hepatocyte growth factor (HGF), play a pivotal role in the activties of tumor cells. A germline missense variant in exon 2 of the MET gene, N375S (rs33917957 A>G), may alter the binding affinity of MET for HGF and thus modify the risk of tumorigenesis. In this...

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Detalles Bibliográficos
Autores principales:	Liu, Yao, Zhang, Qin, Ren, Chuanli, Ding, Yanbing, Jin, Guangfu, Hu, Zhibin, Xu, Yaochu, Shen, Hongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613728/ https://www.ncbi.nlm.nih.gov/pubmed/23554766 http://dx.doi.org/10.7555/JBR.26.20110087

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