Cargando…

Sox2 enhances the tumorigenicity and chemoresistance of cancer stem-like cells derived from gastric cancer

Gastric cancer stem-like cells (GCSCs) have been identified to possess the ability of self-renewal and tumor initiation. However, the mechanisms involved remain largely unknown. Here, we isolated and characterized the GCSCs by side population (SP) sorting procedure and cultured sphere cells (SC) fro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Tian, Zhang, Yajie, Wang, Shouyu, Zhou, Jianwei, Xu, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613730/ https://www.ncbi.nlm.nih.gov/pubmed/23554769 http://dx.doi.org/10.7555/JBR.26.20120045

Ejemplares similares

Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells
por: Vaish, Vivek, et al.
Publicado: (2017)

Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells
por: Pagotto, Anna, et al.
Publicado: (2017)

Genistein-Inhibited Cancer Stem Cell-Like Properties and Reduced Chemoresistance of Gastric Cancer
por: Huang, Weifeng, et al.
Publicado: (2014)

CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer
por: Xu, Wenxia, et al.
Publicado: (2018)

Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness
por: Xue, Jianguo, et al.
Publicado: (2015)

The Prognostic Value of SOX2 Expression in Non-Small Cell Lung Cancer: A Meta-Analysis
por: Chen, Yansu, et al.
Publicado: (2013)

SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer
por: Tang, Jianing, et al.
Publicado: (2021)

SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma
por: Lee, S H, et al.
Publicado: (2014)

Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancer
por: Qian, Xiaoling, et al.
Publicado: (2017)

lncRNA SNHG15 Induced by SOX12 Promotes the Tumorigenic Properties and Chemoresistance in Cervical Cancer via the miR-4735-3p/HIF1a Pathway
por: Yang, Jiang, et al.
Publicado: (2022)

ICG-001 suppresses growth of gastric cancer cells and reduces chemoresistance of cancer stem cell-like population
por: Liu, Yi, et al.
Publicado: (2017)

Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer
por: Zhang, Baotong, et al.
Publicado: (2021)

A SOX2 Reporter System Identifies Gastric Cancer Stem-Like Cells Sensitive to Monensin
por: Pádua, Diana, et al.
Publicado: (2020)

Sox2 is associated with cancer stem-like properties in colorectal cancer
por: Takeda, Koki, et al.
Publicado: (2018)

Chemoresistance in ovarian cancer: exploiting cancer stem cell metabolism
por: Li, Shan-Shan, et al.
Publicado: (2018)

MicroRNA-139 Suppresses the Tumorigenicity of Triple Negative Breast Cancer Cells by Targeting SOX8
por: Dong, Liangliang, et al.
Publicado: (2020)

The Role of HER2 in Self-Renewal, Invasion, and Tumorigenicity of Gastric Cancer Stem Cells
por: Sun, Li-Fei, et al.
Publicado: (2020)

Molecular mechanisms of chemoresistance in gastric cancer
por: Shi, Wen-Jia, et al.
Publicado: (2016)

Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma
por: Shakhova, Olga, et al.
Publicado: (2015)

Knockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosis
por: Li, Lan, et al.
Publicado: (2018)

Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant
por: Hu, L, et al.
Publicado: (2010)

NLRP6, decreased in gastric cancer, suppresses tumorigenicity of gastric cancer cells
por: Wang, Qingqing, et al.
Publicado: (2018)

YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells
por: Jung, Karen, et al.
Publicado: (2014)

Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma
por: Wu, Chengsheng, et al.
Publicado: (2018)

AKAP8L enhances the stemness and chemoresistance of gastric cancer cells by stabilizing SCD1 mRNA
por: Zhang, Ruihong, et al.
Publicado: (2022)

Ca(2+)/calmodulin-dependent protein kinase IIγ enhances stem-like traits and tumorigenicity of lung cancer cells
por: Chai, Shoujie, et al.
Publicado: (2015)

ATOH1 Can Regulate the Tumorigenicity of Gastric Cancer Cells by Inducing the Differentiation of Cancer Stem Cells
por: Han, Myoung-Eun, et al.
Publicado: (2015)

NF‐YA promotes the cell proliferation and tumorigenic properties by transcriptional activation of SOX2 in cervical cancer
por: Yang, Wen‐Ting, et al.
Publicado: (2020)

Cell softness regulates tumorigenicity and stemness of cancer cells
por: Lv, Jiadi, et al.
Publicado: (2020)

Bmi1 Enhances Tumorigenicity and Cancer Stem Cell Function in Pancreatic Adenocarcinoma
por: Proctor, Erica, et al.
Publicado: (2013)

Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
por: Gong, C, et al.
Publicado: (2013)

Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties
por: Lacoste, Benoit, et al.
Publicado: (2017)

Long non-coding RNA GAS5 is critical for maintaining stemness and induces chemoresistance in cancer stem-like cells derived from HCT116
por: Zhou, Xiong, et al.
Publicado: (2020)

SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer
por: Zhu, Yin, et al.
Publicado: (2021)

Cancerous inhibitor of protein phosphatase 2A enhances chemoresistance of gastric cancer cells to oxaliplatin
por: Zhao, Yong-Xun, et al.
Publicado: (2023)

Mechanisms of chemoresistance in cancer stem cells
por: Abdullah, Lissa Nurrul, et al.
Publicado: (2013)

Cytogenetic Evolution of Human Ovarian Cell Lines Associated with Chemoresistance and Loss of Tumorigenicity
por: Struski, Stéphanie, et al.
Publicado: (2003)

EMT and Acquisition of Stem Cell-Like Properties Are Involved in Spontaneous Formation of Tumorigenic Hybrids between Lung Cancer and Bone Marrow-Derived Mesenchymal Stem Cells
por: Xu, Mei-Hua, et al.
Publicado: (2014)

Aberrantly elevated Bmi1 promotes cervical cancer tumorigenicity and tumor sphere formation via enhanced transcriptional regulation of Sox2 genes
por: Xu, Rui, et al.
Publicado: (2019)

Sox12 Is a Cancer Stem-Like Cell Marker in Hepatocellular Carcinoma
por: Zou, Song, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4ide1s16mnrougqhqrgh8ukgm8