Cargando…
The thiazole derivative CPTH6 impairs autophagy
We have previously demonstrated that the thiazole derivative 3-methylcyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone (CPTH6) induces apoptosis and cell cycle arrest in human leukemia cells. The aim of this study was to evaluate whether CPTH6 is able to affect autophagy. By using several...
Autores principales: | Ragazzoni, Y, Desideri, M, Gabellini, C, De Luca, T, Carradori, S, Secci, D, Nescatelli, R, Candiloro, A, Condello, M, Meschini, S, Del Bufalo, D, Trisciuoglio, D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613831/ https://www.ncbi.nlm.nih.gov/pubmed/23470531 http://dx.doi.org/10.1038/cddis.2013.53 |
Ejemplares similares
-
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells
por: Di Martile, Marta, et al.
Publicado: (2016) -
Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells
por: Di Martile, Marta, et al.
Publicado: (2020) -
Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic
Melanoma Cells via the Molecular Chaperone HSP90
por: Trisciuoglio, Daniela, et al.
Publicado: (2010) -
Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer
por: Del Bufalo, Donatella, et al.
Publicado: (2014) -
BCL-X(L) overexpression promotes tumor progression-associated properties
por: Trisciuoglio, Daniela, et al.
Publicado: (2017)