Cargando…
Patterns and rates of exonic de novo mutations in autism spectrum disorders
Autism spectrum disorders (ASD) are believed to have genetic and environmental origins, yet in only a modest fraction of individuals can specific causes be identified(1,2). To identify further genetic risk factors, we assess the role of de novo mutations in ASD by sequencing the exomes of ASD cases...
Ejemplares similares
-
A framework for the detection of de novo mutations in family-based sequencing data
por: Francioli, Laurent C, et al.
Publicado: (2017) -
Analysis of Rare, Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls
por: Liu, Li, et al.
Publicado: (2013) -
GenomeWarp: an alignment-based variant coordinate transformation
por: McLean, Cory Y, et al.
Publicado: (2019) -
De novo Mutations in Schizophrenia Implicate Chromatin Remodeling and Support a Genetic Overlap with Autism and Intellectual Disability
por: McCarthy, Shane E., et al.
Publicado: (2014) -
A framework for variation discovery and genotyping using next-generation DNA sequencing data
por: DePristo, M.A., et al.
Publicado: (2011)