Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

A 5.3 Å resolution, cryo-electron microscopy (cryoEM) map of Chikungunya virus-like particles (VLPs) has been interpreted using the previously published crystal structure of the Chikungunya E1-E2 glycoprotein heterodimer. The heterodimer structure was divided into domains to obtain a good fit to the...

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Detalles Bibliográficos
Autores principales: Sun, Siyang, Xiang, Ye, Akahata, Wataru, Holdaway, Heather, Pal, Pankaj, Zhang, Xinzheng, Diamond, Michael S, Nabel, Gary J, Rossmann, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614025/
https://www.ncbi.nlm.nih.gov/pubmed/23577234
http://dx.doi.org/10.7554/eLife.00435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614025/
https://www.ncbi.nlm.nih.gov/pubmed/23577234
http://dx.doi.org/10.7554/eLife.00435

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