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Thiazolidinedione-Induced Fluid Retention: Recent Insights into the Molecular Mechanisms

Peroxisome proliferator-activated receptor-γ (PPARγ) agonists such as rosiglitazone and pioglitazone are used to improve insulin sensitivity in patients with diabetes mellitus. However, thiazolidinediones induce fluid retention, edema, and sometimes precipitate or exacerbate heart failure in a subse...

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Detalles Bibliográficos
Autores principales: Bełtowski, Jerzy, Rachańczyk, Jolanta, Włodarczyk, Mirosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614122/
https://www.ncbi.nlm.nih.gov/pubmed/23577024
http://dx.doi.org/10.1155/2013/628628