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Thiazolidinedione-Induced Fluid Retention: Recent Insights into the Molecular Mechanisms
Peroxisome proliferator-activated receptor-γ (PPARγ) agonists such as rosiglitazone and pioglitazone are used to improve insulin sensitivity in patients with diabetes mellitus. However, thiazolidinediones induce fluid retention, edema, and sometimes precipitate or exacerbate heart failure in a subse...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614122/ https://www.ncbi.nlm.nih.gov/pubmed/23577024 http://dx.doi.org/10.1155/2013/628628 |