Structure of the hypothetical DUF1811-family protein GK0453 from Geobacillus kaustophilus HTA426

The crystal structure of a conserved hypothetical protein, GK0453, from Geobacillus kaustophilus has been determined to 2.2 Å resolution. The crystal belonged to space group P4(3)2(1)2, with unit-cell parameters a = b = 75.69, c = 64.18 Å. The structure was determined by the molecular-replacement me...

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Detalles Bibliográficos
Autores principales: Padmanabhan, Balasundaram, Nakamura, Yoshihiro, Antonyuk, Svetlana V., Strange, Richard W., Hasnain, S. Samar, Yokoyama, Shigeyuki, Bessho, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Structural Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614154/
https://www.ncbi.nlm.nih.gov/pubmed/23545635
http://dx.doi.org/10.1107/S1744309113003369
Descripción
Sumario:The crystal structure of a conserved hypothetical protein, GK0453, from Geobacillus kaustophilus has been determined to 2.2 Å resolution. The crystal belonged to space group P4(3)2(1)2, with unit-cell parameters a = b = 75.69, c = 64.18 Å. The structure was determined by the molecular-replacement method and was refined to a final R factor of 22.6% (R (free) = 26.3%). Based on structural homology, the GK0453 protein possesses two independent binding sites and hence it may simultaneously interact with two proteins or with a protein and a nucleic acid.

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