Double-ligand modulation for engineering magnetic nanoclusters

Magnetic nanoclusters (MNCs) are agglomerated individual magnetic nanoparticles (MNPs) that show great promise in increasing magnetic resonance imaging (MRI) sensitivity. Here, we report an effective strategy to engineer MNCs based on double-ligand modulation to enhance MRI sensitivity. The oleic ac...

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Detalles Bibliográficos
Autores principales: Kim, Bongjune, Yang, Jaemoon, Lim, Eun-Kyung, Park, Joseph, Suh, Jin-Suck, Park, Hyo Seon, Huh, Yong-Min, Haam, Seungjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614429/
https://www.ncbi.nlm.nih.gov/pubmed/23433032
http://dx.doi.org/10.1186/1556-276X-8-104
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author Kim, Bongjune
Yang, Jaemoon
Lim, Eun-Kyung
Park, Joseph
Suh, Jin-Suck
Park, Hyo Seon
Huh, Yong-Min
Haam, Seungjoo
author_facet Kim, Bongjune
Yang, Jaemoon
Lim, Eun-Kyung
Park, Joseph
Suh, Jin-Suck
Park, Hyo Seon
Huh, Yong-Min
Haam, Seungjoo
author_sort Kim, Bongjune
collection PubMed
description Magnetic nanoclusters (MNCs) are agglomerated individual magnetic nanoparticles (MNPs) that show great promise in increasing magnetic resonance imaging (MRI) sensitivity. Here, we report an effective strategy to engineer MNCs based on double-ligand modulation to enhance MRI sensitivity. The oleic acid-coated individual MNPs self-assembled and then were enveloped by polysorbate 80, using a nanoemulsion method to prepare MNCs. By modulating the amounts of the two ligands, and thus the size and magnetic content of the resultant MNCs, we were able to enormously improve MRI sensitivity.
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spelling pubmed-36144292013-04-04 Double-ligand modulation for engineering magnetic nanoclusters Kim, Bongjune Yang, Jaemoon Lim, Eun-Kyung Park, Joseph Suh, Jin-Suck Park, Hyo Seon Huh, Yong-Min Haam, Seungjoo Nanoscale Res Lett Nano Express Magnetic nanoclusters (MNCs) are agglomerated individual magnetic nanoparticles (MNPs) that show great promise in increasing magnetic resonance imaging (MRI) sensitivity. Here, we report an effective strategy to engineer MNCs based on double-ligand modulation to enhance MRI sensitivity. The oleic acid-coated individual MNPs self-assembled and then were enveloped by polysorbate 80, using a nanoemulsion method to prepare MNCs. By modulating the amounts of the two ligands, and thus the size and magnetic content of the resultant MNCs, we were able to enormously improve MRI sensitivity. Springer 2013-02-22 /pmc/articles/PMC3614429/ /pubmed/23433032 http://dx.doi.org/10.1186/1556-276X-8-104 Text en Copyright ©2013 Kim et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Nano Express
Kim, Bongjune
Yang, Jaemoon
Lim, Eun-Kyung
Park, Joseph
Suh, Jin-Suck
Park, Hyo Seon
Huh, Yong-Min
Haam, Seungjoo
Double-ligand modulation for engineering magnetic nanoclusters
title Double-ligand modulation for engineering magnetic nanoclusters
title_full Double-ligand modulation for engineering magnetic nanoclusters
title_fullStr Double-ligand modulation for engineering magnetic nanoclusters
title_full_unstemmed Double-ligand modulation for engineering magnetic nanoclusters
title_short Double-ligand modulation for engineering magnetic nanoclusters
title_sort double-ligand modulation for engineering magnetic nanoclusters
topic Nano Express
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614429/
https://www.ncbi.nlm.nih.gov/pubmed/23433032
http://dx.doi.org/10.1186/1556-276X-8-104
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