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Promoter Sequence Determines the Relationship between Expression Level and Noise
The ability of cells to accurately control gene expression levels in response to extracellular cues is limited by the inherently stochastic nature of transcriptional regulation. A change in transcription factor (TF) activity results in changes in the expression of its targets, but the way in which c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614515/ https://www.ncbi.nlm.nih.gov/pubmed/23565060 http://dx.doi.org/10.1371/journal.pbio.1001528 |