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Promoter Sequence Determines the Relationship between Expression Level and Noise

The ability of cells to accurately control gene expression levels in response to extracellular cues is limited by the inherently stochastic nature of transcriptional regulation. A change in transcription factor (TF) activity results in changes in the expression of its targets, but the way in which c...

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Detalles Bibliográficos
Autores principales: Carey, Lucas B., van Dijk, David, Sloot, Peter M. A., Kaandorp, Jaap A., Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614515/
https://www.ncbi.nlm.nih.gov/pubmed/23565060
http://dx.doi.org/10.1371/journal.pbio.1001528