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Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition

BACKGROUND: Telomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity. This protection is supported by telomere binding proteins collectively known as the shelterin complex. The shelterin complex protects chromosome ends by suppressing DNA damage response an...

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Detalles Bibliográficos
Autores principales:	Yasaei, Hemad, Gozaly-Chianea, Yaghoub, Slijepcevic, Predrag
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614538/ https://www.ncbi.nlm.nih.gov/pubmed/23521760 http://dx.doi.org/10.1186/2041-9414-4-2

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