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Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts

BACKGROUND: P73 belongs to the p53 family of cell survival regulators with the corresponding locus Trp73 producing the N-terminally distinct isoforms, TAp73 and DeltaNp73. Recently, two studies have implicated the murine Trp73 in the modulation in phospho-tau accumulation in aged wild type mice and...

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Detalles Bibliográficos
Autores principales:	Vardarajan, Badri, Vergote, David, Tissir, Fadel, Logue, Mark, Yang, Jing, Daude, Nathalie, Ando, Kunie, Rogaeva, Ekaterina, Lee, Joseph, Cheng, Rong, Brion, Jean-Pierre, Ghani, Mahdi, Shi, Beipei, Baldwin, Clinton T, Kar, Satyabrata, Mayeux, Richard, Fraser, Paul, Goffinet, André M, George-Hyslop, Peter St, Farrer, Lindsay A, Westaway, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614544/ https://www.ncbi.nlm.nih.gov/pubmed/23414597 http://dx.doi.org/10.1186/1750-1326-8-10

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