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In Situ IgM Production and Clonal Expansion of B-1 Cells in Peritoneal Cavity Promote Elimination of C. albicans Infection in IgH Transgenic Mice with V(H) Derived from a Natural Antibody
B-1 cells are innate-like cells that play important roles in host defense against infection. However, the function of B-1 cells in fungi infection remains unclear. Previously we produced IgH transgenic mice TgV(H)3B4 with V(H) derived from a natural antibody 3B4 that can identify C. albicans, and fo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614557/ https://www.ncbi.nlm.nih.gov/pubmed/23565274 http://dx.doi.org/10.1371/journal.pone.0060779 |