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Exome profiling of primary, metastatic and recurrent ovarian carcinomas in a BRCA1-positive patient

BACKGROUND: Ovarian carcinoma is a common, and often deadly, gynecological cancer. Mutations in BRCA1 and BRCA2 genes are present in at least a fifth of patients. Uncovering other genes that become mutated subsequent to BRCA1/BRCA2 inactivation during cancer development will be helpful for more effe...

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Detalles Bibliográficos
Autores principales:	Zhang, Jian, Shi, Yuhao, Lalonde, Emilie, Li, Lili, Cavallone, Luca, Ferenczy, Alex, Gotlieb, Walter H, Foulkes, William D, Majewski, Jacek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614563/ https://www.ncbi.nlm.nih.gov/pubmed/23522120 http://dx.doi.org/10.1186/1471-2407-13-146

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