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Association Study: The Aminopeptidase a Gene and Essential Hypertension

Aminopeptidase A (APA) cleaves the N-terminal aspartyl acid residue of angiotensin II (Ang II) to produce angiotensin III (Ang III). It has been reported that the APA knockout mouse exhibits elevated blood pressure. Therefore, the APA gene is thought to be a susceptibility gene for essential hyperte...

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Detalles Bibliográficos
Autores principales: Sano, Morihiko, Kuroi, Nobuhiro, Nakayama, Tomohiro, Sato, Naoyuki, Izumi, Yoichi, Soma, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614582/
https://www.ncbi.nlm.nih.gov/pubmed/23674950