Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981

To study some biological and molecular properties of nine DENV-2 strains isolated during the 1981 Cuban epidemic, temperature sensitivity, viral plaque size, the kinetic of virus replication in newborn mice inoculated by intracerebral route, the influence of pH medium on virus-cell attachment phase...

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Detalles Bibliográficos
Autores principales: González, Lester, Álvarez, Mayling, del Rosario, Delfina, Pavón, Alequis, Prado, Irina, Díaz, Joel, Morier, Luis, Guzmán, María G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614631/
https://www.ncbi.nlm.nih.gov/pubmed/23675036
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author González, Lester
Álvarez, Mayling
del Rosario, Delfina
Pavón, Alequis
Prado, Irina
Díaz, Joel
Morier, Luis
Guzmán, María G.
author_facet González, Lester
Álvarez, Mayling
del Rosario, Delfina
Pavón, Alequis
Prado, Irina
Díaz, Joel
Morier, Luis
Guzmán, María G.
author_sort González, Lester
collection PubMed
description To study some biological and molecular properties of nine DENV-2 strains isolated during the 1981 Cuban epidemic, temperature sensitivity, viral plaque size, the kinetic of virus replication in newborn mice inoculated by intracerebral route, the influence of pH medium on virus-cell attachment phase and the restriction enzyme pattern were studied. Strains were classified in two patterns according to temperature sensitivity, plaque size, and virus replication in mouse brain and cell culture and restriction enzymatic pattern the changes observed differentiate clearly the strains isolated at the beginning and at the end of the epidemic suggesting that viruses with different characteristics circulated.
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spelling pubmed-36146312013-05-01 Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981 González, Lester Álvarez, Mayling del Rosario, Delfina Pavón, Alequis Prado, Irina Díaz, Joel Morier, Luis Guzmán, María G. Int J Biomed Sci Article To study some biological and molecular properties of nine DENV-2 strains isolated during the 1981 Cuban epidemic, temperature sensitivity, viral plaque size, the kinetic of virus replication in newborn mice inoculated by intracerebral route, the influence of pH medium on virus-cell attachment phase and the restriction enzyme pattern were studied. Strains were classified in two patterns according to temperature sensitivity, plaque size, and virus replication in mouse brain and cell culture and restriction enzymatic pattern the changes observed differentiate clearly the strains isolated at the beginning and at the end of the epidemic suggesting that viruses with different characteristics circulated. Master Publishing Group 2007-06 /pmc/articles/PMC3614631/ /pubmed/23675036 Text en © González et al. Licensee Master Publishing Group http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
González, Lester
Álvarez, Mayling
del Rosario, Delfina
Pavón, Alequis
Prado, Irina
Díaz, Joel
Morier, Luis
Guzmán, María G.
Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981
title Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981
title_full Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981
title_fullStr Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981
title_full_unstemmed Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981
title_short Biological and Molecular Properties of Dengue 2 Strains Isolated during the DHF/DSS Cuban Epidemic, 1981
title_sort biological and molecular properties of dengue 2 strains isolated during the dhf/dss cuban epidemic, 1981
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614631/
https://www.ncbi.nlm.nih.gov/pubmed/23675036
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