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QSAR Study on a Series of Protein Tyrosine Phosphatase 1B Inhibitors

As a therapeutic target, protein tyrosine phosphatase 1B (PTP1B) has received considerable attention for the treatment of diabetes mellitus. A QSAR study using substituted monocyclic and polycyclic thiophene derivatives, recently reported as potent PTP1B inhibitors, was carried out. More than 60 phy...

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Detalles Bibliográficos
Autores principales: Mehta, Rajendra S., Prajapati, Hetal R., Thakkar, Dinesh V., Brahmkshatriya, Pathik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614718/
https://www.ncbi.nlm.nih.gov/pubmed/23675100