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Pamidronate Alters the Growth Plate in the Oim Mouse Model for Osteogenesis Imperfecta

Bisphosphonates alleviate bone pain and fractures associated with osteogenesis imperfecta (OI). Using the oim mouse model to simulate variations in OI severity, the effect of pamidronate on bone growth was assessed. Homozygous (oim/oim) and heterozygous (oim/wt) mice from 4 to 12 weeks of age were g...

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Detalles Bibliográficos
Autores principales: Evans, K. D., Sheppard, L. E., Rao, S. H., Martin, R. B., Oberbauer, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Master Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614807/
https://www.ncbi.nlm.nih.gov/pubmed/23675157