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Statistical Modeling of Lung Cancer: Answering Relative Questions
The objective of this paper is to perform parametric and nonparametric analysis to address some very important questions concerning lung cancer utilizing real lung cancer data: What is the probabilistic nature of mortality time in ex-smoker lung cancer patients and non-smoker lung cancer patients, f...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Master Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614812/ https://www.ncbi.nlm.nih.gov/pubmed/23675223 |
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author | Cong, Chunling Kepner, James Tsokos, Chris. P. |
author_facet | Cong, Chunling Kepner, James Tsokos, Chris. P. |
author_sort | Cong, Chunling |
collection | PubMed |
description | The objective of this paper is to perform parametric and nonparametric analysis to address some very important questions concerning lung cancer utilizing real lung cancer data: What is the probabilistic nature of mortality time in ex-smoker lung cancer patients and non-smoker lung cancer patients, for female, male, and the totality of female and male patients? Is there significant difference of mortality time between ex-smoker and non-smoker patients? For ex-smokers, are there any differences with respect to the key variables such as mortality time, cigarettes per day (CPD), and duration of smoking between female and male patients? For non-smokers, can we notice a difference in mortality time between female and male patients? Can we accurately predict mortality time given information on CPD, starting time and quitting time for a specific lung cancer patient who smokes? Thus best fitting probability distributions are identified and their parameters are estimated. Mean mortality times are compared between non-smokers and ex-smokers, female non-smokers and male non-smokers, and female ex-smokers and male ex-smokers. Important entities related to lung cancer mortality time, such as cigarettes per day (CPD), and duration of smoking (DUR), are compared between female and male ex-smoker lung cancer patients. Finally, a model is developed to predict the mortality time of ex-smokers with a high degree of accuracy. |
format | Online Article Text |
id | pubmed-3614812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Master Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-36148122013-05-01 Statistical Modeling of Lung Cancer: Answering Relative Questions Cong, Chunling Kepner, James Tsokos, Chris. P. Int J Biomed Sci Article The objective of this paper is to perform parametric and nonparametric analysis to address some very important questions concerning lung cancer utilizing real lung cancer data: What is the probabilistic nature of mortality time in ex-smoker lung cancer patients and non-smoker lung cancer patients, for female, male, and the totality of female and male patients? Is there significant difference of mortality time between ex-smoker and non-smoker patients? For ex-smokers, are there any differences with respect to the key variables such as mortality time, cigarettes per day (CPD), and duration of smoking between female and male patients? For non-smokers, can we notice a difference in mortality time between female and male patients? Can we accurately predict mortality time given information on CPD, starting time and quitting time for a specific lung cancer patient who smokes? Thus best fitting probability distributions are identified and their parameters are estimated. Mean mortality times are compared between non-smokers and ex-smokers, female non-smokers and male non-smokers, and female ex-smokers and male ex-smokers. Important entities related to lung cancer mortality time, such as cigarettes per day (CPD), and duration of smoking (DUR), are compared between female and male ex-smoker lung cancer patients. Finally, a model is developed to predict the mortality time of ex-smokers with a high degree of accuracy. Master Publishing Group 2011-03 /pmc/articles/PMC3614812/ /pubmed/23675223 Text en © Chunling Cong et al. Licensee Master Publishing Group http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Article Cong, Chunling Kepner, James Tsokos, Chris. P. Statistical Modeling of Lung Cancer: Answering Relative Questions |
title | Statistical Modeling of Lung Cancer: Answering Relative Questions |
title_full | Statistical Modeling of Lung Cancer: Answering Relative Questions |
title_fullStr | Statistical Modeling of Lung Cancer: Answering Relative Questions |
title_full_unstemmed | Statistical Modeling of Lung Cancer: Answering Relative Questions |
title_short | Statistical Modeling of Lung Cancer: Answering Relative Questions |
title_sort | statistical modeling of lung cancer: answering relative questions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614812/ https://www.ncbi.nlm.nih.gov/pubmed/23675223 |
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