Cargando…

MafA is a Key Molecule in Glucose and Energy Balance in the Central Nervous System and Peripheral Organs

MafA is a strong transactivator of insulin in pancreatic β cells. Elucidating the profile of MafA action in organs other than the pancreas is essential. We established an mRNA interference technique that modifies the level of target mRNAs in mice in vivo. After rapidly injecting MafA-siRNA, the resu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsuchiya, Mariko, Tsuchiya, Ken, Yasuda, Kazuki, Fujita, Mikiko, Takinishi, Akira, Furukawa, Maiko, Nitta, Kosaku, Maeda, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Master Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614815/ https://www.ncbi.nlm.nih.gov/pubmed/23675216

Ejemplares similares

MafA Is Required for Postnatal Proliferation of Pancreatic β-Cells
por: Eto, Koki, et al.
Publicado: (2014)

Loss of MafA and MafB expression promotes islet inflammation
por: Singh, Tania, et al.
Publicado: (2019)

MafB Maintains β-Cell Identity under MafA-Deficient Conditions
por: Deng, Zhaobin, et al.
Publicado: (2022)

MafA and MafB Regulate Genes Critical to β-Cells in a Unique Temporal Manner
por: Artner, Isabella, et al.
Publicado: (2010)

MafB Is Important for Pancreatic β-Cell Maintenance under a MafA-Deficient Condition
por: Xiafukaiti, Gulibaikelamu, et al.
Publicado: (2019)

Correction: MafA Is Required for Postnatal Proliferation of Pancreatic β-Cells
Publicado: (2014)

MafA Expression Preserves Immune Homeostasis in Human and Mouse Islets
por: Singh, Tania, et al.
Publicado: (2018)

An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition
por: Deng, Zhaobin, et al.
Publicado: (2020)

MafA Regulation in β-Cells: From Transcriptional to Post-Translational Mechanisms
por: Liang, Jiani, et al.
Publicado: (2022)

MafA and MafB Regulate Pdx1 Transcription through the Area II Control Region in Pancreatic β Cells
por: Vanhoose, Amanda M., et al.
Publicado: (2008)

Regulation of MafA Expression in Pancreatic β-Cells in db/db Mice With Diabetes
por: Matsuoka, Taka-aki, et al.
Publicado: (2010)

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth
por: Hang, Yan, et al.
Publicado: (2014)

The outer-membrane protein MafA of Neisseria meningitidis constitutes a novel protein secretion pathway specific for the fratricide protein MafB
por: Arenas, Jesús, et al.
Publicado: (2020)

Insulin Transactivator MafA Regulates Intrathymic Expression of Insulin and Affects Susceptibility to Type 1 Diabetes
por: Noso, Shinsuke, et al.
Publicado: (2010)

The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification
por: Luan, Cheng, et al.
Publicado: (2019)

Comprehensive Search for GPCR Compounds which Can Enhance MafA and/or PDX-1 Expression Levels Using a Small Molecule Compound Library
por: Kaneto, Hideaki, et al.
Publicado: (2023)

Reprogramming of Various Cell Types to a Beta-Like State by Pdx1, Ngn3 and MafA
por: Akinci, Ersin, et al.
Publicado: (2013)

MafA promotes the reprogramming of placenta-derived multipotent stem cells into pancreatic islets-like and insulin(+) cells
por: Chiou, Shih-Hwa, et al.
Publicado: (2011)

MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes
por: Ganic, Elvira, et al.
Publicado: (2016)

Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice
por: Zhu, Ke, et al.
Publicado: (2020)

TAT-Mediated Transduction of MafA Protein In Utero Results in Enhanced Pancreatic Insulin Expression and Changes in Islet Morphology
por: Vargas, Nancy, et al.
Publicado: (2011)

Generation of Insulin-Expressing Cells in Mouse Small Intestine by Pdx1, MafA, and BETA2/NeuroD
por: Lee, So-Hyun, et al.
Publicado: (2017)

Expression Profiling of Pdx1, Ngn3, and MafA in the Liver and Pancreas of Recovering Streptozotocin-Induced Diabetic Rats
por: Al-Adsani, Amani M., et al.
Publicado: (2022)

Specific reprogramming of alpha cells to insulin-producing cells by short glucagon promoter-driven Pdx1 and MafA
por: Guo, Ping, et al.
Publicado: (2023)

Sphingosine‐1‐phosphate acts as a key molecule in the direct mediation of renal fibrosis
por: Shiohira, Shunji, et al.
Publicado: (2013)

A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34(+) Cells
por: Reebye, Vikash, et al.
Publicado: (2013)

Cooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta Cells
por: Arcidiacono, Biagio, et al.
Publicado: (2015)

The Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis
por: Wu, Rui, et al.
Publicado: (2022)

Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA
por: Akinci, Ersin, et al.
Publicado: (2012)

Protein therapy using MafA fused to a polyarginine transduction domain attenuates glucose levels of streptozotocin-induced diabetic mice
por: Lu, Jun, et al.
Publicado: (2017)

Transcriptome analysis of human brain microvascular endothelial cells response to Neisseria meningitidis and its antigen MafA using RNA-seq
por: Káňová, Evelína, et al.
Publicado: (2019)

MafA Overexpression: A New Efficient Protocol for In Vitro Differentiation of Adipose-Derived Mesenchymal Stem Cells into Functional Insulin-Producing Cells
por: Dayer, Dian, et al.
Publicado: (2019)

Pax4 synergistically acts with Pdx1, Ngn3 and MafA to induce HuMSCs to differentiate into functional pancreatic β-cells
por: Zhang, Ting, et al.
Publicado: (2019)

A low-protein maternal diet during gestation affects the expression of key pancreatic β-cell genes and the methylation status of the regulatory region of the MafA gene in the offspring of Wistar rats
por: Sosa-Larios, Tonantzin C., et al.
Publicado: (2023)

Ebselen Treatment Prevents Islet Apoptosis, Maintains Intranuclear Pdx-1 and MafA Levels, and Preserves β-Cell Mass and Function in ZDF Rats
por: Mahadevan, Jana, et al.
Publicado: (2013)

The m(6)A Methyltransferase METTL3 Ameliorates Methylglyoxal-Induced Impairment of Insulin Secretion in Pancreatic β Cells by Regulating MafA Expression
por: Cheng, Yi, et al.
Publicado: (2022)

The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination
por: Zhang, Zubin, et al.
Publicado: (2023)

Comprehensive identification of high-frequency and co-occurring Mafa-B, Mafa-DQB1, and Mafa-DRB alleles in cynomolgus macaques of Vietnamese origin
por: Ling, Fei, et al.
Publicado: (2012)

Generation of Functional Insulin-Producing Cells from Neonatal Porcine Liver-Derived Cells by PDX1/VP16, BETA2/NeuroD and MafA
por: Ham, Dong-Sik, et al.
Publicado: (2013)

Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors
por: Koblas, Tomas, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_t91d767h7d2446uajo8f54hu18